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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B1
All Species:
33.64
Human Site:
S72
Identified Species:
61.67
UniProt:
O75533
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75533
NP_036565.2
1304
145830
S72
D
D
D
D
D
Y
S
S
S
T
S
L
L
G
Q
Chimpanzee
Pan troglodytes
XP_516006
1379
153963
S147
D
D
D
D
D
Y
S
S
S
T
S
L
L
G
Q
Rhesus Macaque
Macaca mulatta
XP_001086317
1397
156322
S165
D
D
D
D
D
Y
S
S
S
T
S
L
L
G
Q
Dog
Lupus familis
XP_857149
1312
146628
S72
D
D
D
D
D
Y
S
S
S
T
S
L
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB9
1304
145798
S72
D
D
D
D
D
Y
S
S
S
T
S
L
L
G
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421912
1383
154834
S154
D
D
D
D
D
Y
P
S
T
S
L
L
G
Q
K
Frog
Xenopus laevis
O57683
1307
146196
S72
D
D
D
D
D
V
S
S
A
T
F
E
Q
K
K
Zebra Danio
Brachydanio rerio
XP_684311
1315
147162
S75
D
D
D
D
E
D
S
S
T
S
L
L
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623732
1315
147662
T76
E
D
E
D
Y
E
P
T
T
F
S
T
N
K
R
Nematode Worm
Caenorhab. elegans
NP_497853
1322
147305
D77
E
E
D
D
V
D
E
D
S
M
P
S
V
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323970
1267
141858
A60
E
V
G
L
N
E
V
A
Q
K
L
A
S
Y
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201232
1269
141432
T59
E
D
D
A
N
L
D
T
T
G
S
L
V
A
Q
Baker's Yeast
Sacchar. cerevisiae
P49955
971
110009
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
93.3
99.3
N.A.
99.9
N.A.
N.A.
N.A.
93.7
96.6
93.7
N.A.
N.A.
82.4
65.1
N.A.
Protein Similarity:
100
94.5
93.3
99.3
N.A.
100
N.A.
N.A.
N.A.
93.7
98.3
96.4
N.A.
N.A.
88.9
76.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
53.3
53.3
46.6
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
73.3
66.6
80
N.A.
N.A.
53.3
46.6
N.A.
Percent
Protein Identity:
68.4
N.A.
N.A.
68.3
40.4
N.A.
Protein Similarity:
79.3
N.A.
N.A.
79.1
53.1
N.A.
P-Site Identity:
0
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
66.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
8
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
77
77
77
54
16
8
8
0
0
0
0
0
0
0
% D
% Glu:
31
8
8
0
8
16
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
0
0
8
39
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
31
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
24
62
39
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
24
47
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
54
62
47
16
54
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
31
47
0
8
0
0
8
% T
% Val:
0
8
0
0
8
8
8
0
0
0
0
0
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
47
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _